What is autism? What are the symptoms of autism? Does it run in families or what causes it? These questions and more will be answered by 2022 with all-new research.
The “which parent carries autism gene” is a question that has been on the minds of parents for a while. The science in 2022 will answer this question.
Consider DNA to be the body’s recipe book. The information contained inside each cell determines how you appear, develop, and feel. Things that occurs outside of your body may impact, and sometimes even modify, that information.
Because of the complexity of genetics, simple questions like “Is autism genetic?” are difficult to answer. There are several elements at play.
Several noteworthy research have come to a close in the past several years. Many of them imply that autism is, at least in part, hereditary. Others emphasize how little is known about the impact of genes in autism.
We’ll go through what scientists have to say when asked whether autism is inherited. We’ll also point out what additional we need to know before we can definitely answer queries.
Genes in Autism: What Role Do They Play?
Parents pass on their genes to their offspring. Two sets of genes struggle for supremacy in each kid. Sometimes children have the same problems as their parents. Siblings might share genetic features as well. Family studies reveal a lot about how heredity plays a role in autism.
We’ve known for years that autism is a genetic condition that may be passed down from parents to children. That characteristic was underlined in the first research on identical twins, which was published in 1977. Researchers believe that if one identical twin has autism, the other is 80 percent certain to have it as well. If the twins are fraternal, the risk is reduced to about 40%.
Children with autism spectrum disorder are known to have various genetic-based diseases, such as:
- 22q deletion syndrome is a condition in which one of the chromosome
- Angelman syndrome is a condition that affects people.
- THE SYNDROME OF THE CHARGE
- Cornelia de Lange syndrome is a condition in which a person has Cornelia de Lange
- Down syndrome is a condition in which a person is born
- Duchenne muscular dystrophy (DMD) is a kind of muscular dystrophy that (DMD).
- Fragile X syndrome is a condition that affects people of all ages.
- Prader-Willi syndrome is a genetic disorder (PWS).
- Rett syndrome is a neurological disorder.
- Smith-Lemli-Opitz syndrome is a condition in which a person has Smith-Lemli-O (SLOS).
- Smith-Magenis syndrome is a condition that affects both men and women (SMS).
- The Sotos syndrome is a condition in which a person suffers from
- Tuberous sclerosis is a disease that affects the nervous system.
According to studies, around 20% of children with ASD have this condition. Missing or excess sections of DNA, as well as other sorts of abnormalities, cause the majority of the illnesses.
It’s conceivable that autism and these other genetic disorders are connected, and that they pass down from parent to kid in a way that researchers can identify.
There are a lot of genes involved.
Some genetic disorders are straightforward, and they are caused by a single uncommon component located in one strand of DNA. Autism is quite different, and its intricacy makes it much more difficult to diagnose.
Researchers revealed the findings of a big investigation in January 2020, which included:
- A huge research group. Over 35,000 individuals submitted samples for testing.
- ASD information. Almost 12,000 of the 35,000 individuals had autistic spectrum disorder.
- Sequencing of genes. Rare mutations were discovered using testing techniques that were previously disguised by other approaches.
More than 102 genes were linked to the risk of autism, according to the findings. This is a large number, and scientists believe the genes are intertwined and intermingled.
Some of them are linked to other types of developmental delays. Others seem to make neurodevelopmental problems more likely.
Because researchers don’t yet understand how the genes function, parents can’t just go into a lab and request an autism gene test. There’s much too much data to go through, and there’s still a lot we don’t know.
However, this research implies that a combination of genes may increase the chance of autism. Researchers may be able to use this information to find new strategies to treat, and maybe even cure, ASD.
More investigation is required.
It’s critical to understand how many genes are linked to autism risk. We just don’t know enough about autism spectrum disorder yet, according to researchers, to put our genetics knowledge to use.
Genes, according to some experts, explain how cells function and also reveal how damage generates disease risk. There are several non-genetic risk factors for ASD, including:
- Mitochondria. These microscopic entities supply energy to the organism and contain their own DNA. People with ASD often have abnormal mitochondrial function, which might set off a chain reaction that leads to autistic symptoms.
- Susceptibility throughout development. Everyone’s genes and environment are intertwined. A person with the correct set of genes pushed toward the proper prompt may acquire ASD, but someone who avoids the trigger may never develop the condition.
- Environment. Factors such as twin pregnancies, insufficient folate consumption during pregnancy, and others may increase the chance of autism.
All of these risk factors might either overshadow the function of genetics in autism risk or they could be a piece of the jigsaw that clarifies the role of genetics. To resolve these problems, further scientific research is needed.
Autism may also emerge in persons who have no family history of the illness, according to researchers. In fact, they claim that around 30% of instances are like this. What does it signify in terms of a “autism gene” if the condition occurs in persons who have few or no genetic vulnerabilities? In 2021, we will not know the answers to this question.
Every day, a team of brilliant researchers sits down with slides, samples, and data to try to figure out how our genetic information impacts autism risk. However, sometimes the outcomes raise more issues than they solve. We want a clear image, but it isn’t accessible now.
What Is the Importance of Genetic Research?
Why do experts keep trying to figure out whether autism is hereditary if it’s so difficult? Their efforts may seem useless, but the outcomes are crucial for families, clinicians, and autistic children.
Families, for example, have long been concerned about increased autism risk caused by common activities. They are concerned about:
- Dietary habits of a mother.
- Dietary habits of a youngster.
- Infections, such as the influenza virus.
Parents might become so concerned and agitated that they neglect to take life-saving measures, such as vaccinating their children and introducing them to nutritious diets. Genetic research may provide some alleviation.
In a big study published in 2019, researchers discovered that genes, not the environment, were responsible for 80% of autism risk. This information was widely disseminated, and it allayed some concerns and misgivings. The announcement may have brought solace to parents who blamed themselves for their child’s ASD.
Gene research may also lead to therapies and cures. A North Carolina research team, for example, is focusing on both detection and cure technologies. One of the studies looks on genetic testing so that parents can detect the illness in their children before symptoms develop. The other looks at gene splicing, so any damaged data is erased before any issues arise.
This is ground-breaking research, and we may have to wait years to find out whether the ideas can be translated into practical solutions. The researchers still have a lot more work to do before they can begin working with families on therapy.
They couldn’t imagine a day when early detection and therapy were available to families without genetic research. They must build on the efforts of others.
Other researchers are considering customized medicine as a result of the findings. They claim that discovering gene sequencing abnormalities might aid physicians in developing highly individualized treatment regimes for their patients. The tablets taken by one individual would be considerably different from those taken by another.
This work is, once again, brand new and based on cutting-edge research. Researchers will need a lot more time to finalize and implement their ideas, but the possibilities are intriguing.
What Can Families Do Immediately?
Gene splicing isn’t something your family doctor can help you with. Some doctors are unable to give genetic counseling. If you have autism and are thinking about starting a family, keep in mind that your children may have the same condition as you. If you don’t have autism but someone in your family does, your child’s risks may be increased.
Keep an eye on the outcomes of research if you have a kid or a loved one with autism. Consult your doctor if you have any concerns. Look for methods to donate to autism research organisations. The more we learn about this condition, the better off we will be.
The “autism genes identified” is a new study that has been released. This study shows that autism could be genetic and that genetics play a big role in the development of the disorder.
- is autism genetic or hereditary
- what causes autism
- what is the most common known genetic cause of autism spectrum disorder
- autism genes list
- autism genetic testing for parents
Janice is a Board Certified Behavior Analyst. She graduated from the University of British Columbia with a Bachelor of Arts in Psychology and Special Education. She also holds a Master of Science in Applied Behaviour Analysis (ABA) from Queen’s University, Belfast. She has worked with and case managed children and youth with autism and other intellectual and/or developmental disabilities in home and residential setting since 2013.